RESTplus evolved from REST (Resting-State fMRI Data Analysis Toolkit). It is based on Matlab and SPM8. RESTplus includes four main modules, i.e., pipeline, statistical analysis, utilities and viewer.
The pipeline (either fixed or flexible) module provides a very easy way for data processing. After arrangethe DICOM or NIFTI filesand click a few buttons to set parameters, the pipeline (or flexible) module will automatically calculate each processing step and give you all the processed data. The pipeline and flexible module can perform slice timing, realign, reorient, normalize, smooth, detrend, filter, nuisance covariates regression, Functional Connectivity (FC), Regional Homogeneity (ReHo), Amplitude of Low-Frequency Fluctuation (ALFF), fractional ALFF (fALFF), Granger causality, degree centrality, voxel-mirrored homotopic connectivity (VMHC), and percent amplitude of fluctuation (PerAF).
You can also use RESTplus to perform statistical analysis, view your data, perform Monte Carlo simulation (similar to AlphaSim in AFNI), perform Gaussian random field theory multiple comparison correction like easythresh in FSL, calculate your images, regress out covariates, extract ROI time courses, reslice images, calculate intraclass correlation, perform quality assurance, normalize PET data, inverse data into original space, and sort DICOM files. RESTplus also includes ASL toolbox.
JIA Xi-Ze, Wang Jue, Liao Wei, Zhang Han, Liu Dong-qiang, Ji Gong-jun, Gao Zhong-zhan, Li Xun, Huang Hui-yuan, Wang Ze, Yan Chao-gan, Song Xiao-wei, Zang Yu-feng
New features of RESTplus V1.1 (released 20160122)
1. SPM12 Compatible (JIA Xi-Ze)
2. Added ASL toolbox for pcasl and 3D ASL (WANG Ze and JIA Xi-Ze)
3. Updated rp_spm_write_vol.m and rp_spm_read_vols.m from SPM5 to SPM12 (JIA Xi-Ze and LI Xun).
4. Spatial correlation of images in Imaging Calculator, supporting mask selection (JIA Xi-Ze; Thanks the report by JIAO Fang-Yang).
5. Added standardized effect size for t-tests (GAO Zhong-Zhan and JIA Xi-Ze)
6. Fixed a bug when subject ID of dicom header includes ‘-’ or ‘:’. ‘_’ and ‘:’ will be replaced by ‘_’. (JIA Xi-Ze; Thanks report of LIU Yan)
New features of RESTplus V1.0 beta release 151028:
1 Added pipeline module (JIA Xi-Ze)
2 Added flexible module (JIA Xi-Ze)
3 Added quality assurance module (JIA Xi-Ze)
4 Added REST inverse module (JIA Xi-Ze)
5 Added PET Normalize module (JIA Xi-Ze)
6 Added REST Intraclass correlation module (JIA Xi-Ze)
7 Added ASL toolbox for pasl (Wang Ze and JIA Xi-Ze)
8 fix a bug in of NIfTI nii to NIfTI pairs. (Li Xun and JIA Xi-Ze)
9 Nuisance covariates regression can add mean back (JIA Xi-Ze)
10 Module of percent amplitude of fluctuation (PerAF) has been added. (JIA Xi-Ze)
Thanks a lot for your email to JIA Xi-Ze (firstname.lastname@example.org) for any suggestion.