October 2013

Challenges of meta-analysis on resting-state fMRI studies

    Activation likelihood estimation (ALE) is a very good method for task fMRI meta-analysis studies (including both within-group between-condition activation difference and between-group activation difference). Although the design of task fMRI studies varies a lot from study to study, most task fMRI studies use very similar GLM method and focus on the local activity of, rather than the relationship between, brain regions. There have been many meta-analysis task fMRI studies.