a question about vbm

 Hi, Yan,
I use VBM8 to process T1 data in which default setting is selected. But I have a question:  ICBM template was firstly applied during unified segement, and another template derived from 550 healthy controls was then used during normalization. Is it reasonable to use two different templates in a study? can I change the second template above into my newly-created template? if I can, do I need to make other settings in VBM8?
Thanks!