SPM8,VBM的处理分析

 请各位老师指教。问题如下:在一篇比较长期音乐训练对大脑灰质密度产生影响的文章中,提到提取每个被试发生灰质密度改变的每个cluster提取一个EVs值(mean first eigenvariates),这个值使用SPM8提取的,然后用EVs值与两个音乐判断的行为指标做多元回归。

请问此处的EVs值是什么意思?有什么作用?用SPM8如何提取?

 ReHo measures fMRI BOLD signals' similarity (or accordance) among one voxel and its neighbouring voxels (in three dimension, 26 voxels). For each voxel, ReHo value can be calculated, therefore, we can get a "ReHo" brain, this is a local functional connectivity measurement.  For details please refer to Zang et al., 2004, NeuroImage, "Regional homogeneity approach ..."

 fALFF is a variation of ALFF. ALFF measures fMRI BOLD signals' fluctuation. In each voxel, there will be a BOLD time series, the amplitude of its fluctuation (or the variation of the fluctuation) in a certain frequency band (we usually use 0.01-0.08 Hz as its the main band for resting-state functional connectivity) produces ALFF.    Therefore, fALFF measures the fluctuation characteristic for each voxel. Please see Zang et al., 2007, Brain & Development, "Altered baseline brain activity in children ..."

 

So far as I know, SPM uses "VOI" function to extract EVs. To use it, firstly you should get the spm result using "Result" in SPM, then, in the result view control window, you can find "VOI".   In SPM 8 manual, search "VOI" you also can get the detailed answer.  EVs is the first eigen vector obtained from Principle Component Analysis (PCA), basically, it is similar as the "weighted average". The first EV is often regarded as the "summary of the data".

So far as I know, SPM uses "VOI" function to extract EVs. To use it, firstly you should get the spm result using "Result" in SPM, then, in the result view control window, you can find "VOI".   In SPM 8 manual, search "VOI" you also can get the detailed answer.  EVs is the first eigen vector obtained from Principle Component Analysis (PCA), basically, it is similar as the "weighted average". The first EV is often regarded as the "summary of the data".