One Sample T Test

Does it make any sense to do this on sm-1_ReHo data for a group of subjects? OR does ReHo only make sense in a comparison (i.e. paired t test or two way test) to some other baseline/condition?
When I tried to make a oneway test it basically gave me a whole brain activation.

Hi!
set sm-1_Reho compare to 0
or set smReho compare to 1
You can see default mode network regions showed hign Reho.
"whole brain activiation"? Compare smReho to 0?

Thanks for the response.
Can you please explain why a one sample t test would yield whole brain activation even when the threshold is very high?

mReHo is the raw ReHo value divided by the global mean value.
Thus, most mReHo value could be near "1". If you compare to "0", then you can find high value everywhere.
Best wishes!