RE: long mixed session of rest and task

A long session, 22 minutes: Resting state 9 minutes, and then a blocked design (2 minutes task + 30s rest) 13 minutes. The questions are:
(1) Is the head motion a concern?
(2) Can the 9-minutes rest be used as a baseline for the data analysis of the blocked design?

My answer:
(1) Yes. There may be more head motion for such a long session. But occasionally, a long rest is necessary (e.g., epilepsy and sleep study).
(2) I don't recommend. Event for acupuncture study, I don't recommend to use a long rest as a baseline to do GLM (e.g., paired t-test) because the drift and order effect should be considered.

Yufeng

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