meanings about REST software

Submitted by wanghui on Thu, 12/10/2009 - 11:54

i have run DPARSF successfully ,gets the result of my data about :REHO ALFF fALFF.I want to know when i run the REST software,knock in ALFF,then  power spectrum.i move in the ALFF result of one data,choose one coordinate point,for example: x:2,y:2,z:2.then i see a value under it,different for each coordinate.what does that value mean?is it the ALFF value of that particular coorinate point,how the software calculate the value from the ALFF reault?thanks very much.i do need to know that.wish to get the answer soon.

Submitted by YAN Chao-Gan on Thu, 12/10/2009 - 14:45

Hi! Please see more details in Zang YF, He Y, Zhu CZ, Cao QJ, Sui MQ, Liang M, Tian LX, Jiang TZ, Wang YF. 2007. Altered baseline brain activity in children with ADHD revealed by resting-state functional MRI. Brain Dev. 29:83-91.
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Next, the filtered time series was transformed to a frequency domain with a fast Fourier transform (FFT) and the power spectrum was then obtained. Since the power of a given frequency is proportional to the square of the amplitude of this frequency component of the original time series in the time domain, the square root was calculated at each frequency of the power spectrum and the averaged square root was obtained across 0.01–0.08 Hz at each voxel. This averaged square root was taken as the ALFF.
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Submitted by wanghui on Thu, 12/10/2009 - 19:21

thanks for ur relay in time.i do want to read that article,but i have problem to get the full article on pubmed,because it need to be paid.can u send me by email?thanks very much.

Submitted by YAN Chao-Gan on Thu, 12/10/2009 - 22:42

Hi!
Please find it in your mail box.
Best wishes!

Submitted by wanghui on Mon, 12/14/2009 - 21:24

thanks for your mail,i read your article,it's good and quiet useful for me.but my case is different.we take 5 different time points resting-state fMRI image for one patient.want to see if there are any change during the recovery (within one week to  half a year later. )i have already get the ALFF results for each patients in different time points,but i do not know how to run repeated measurement design use SPM,there are just one sample-t test and two sample-t test in your video.so can it be done on SPM?and How ?thanks very much.

Submitted by YAN Chao-Gan on Wed, 12/16/2009 - 10:54

Hi!
Please see http://www.fil.ion.ucl.ac.uk/~wpenny/publications/rik_anova.pdf to know more about how to perform repeated measure analysis.
However, in my opinion, you still need to have a hypothesis before testing the 5 time points.
Could Prof. Zang give more comments on this issue please? Thanks!
Best wishes!